Loganin alleviates LPS‐activated intestinal epithelial inflammation by regulating TLR4/NF‐κB and JAK/STAT3 signaling pathways

Loganin alleviates LPS‐activated intestinal epithelial inflammation by regulating TLR4/NF‐κB and JAK/STAT3 signaling pathways

Abstract Inflammatory bowel disease (IBD) is a chronic, recurrent gastrointestinal inflammation that affects millions of people around the world. Loganin, an iridoid glycoside, has shown the anti‐inflammatory effects. However, the effect of loganin on IBD and its underlying molecular mechanism are n...

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Bibliographic Details
Main Authors: Jia‐Wen Wang, Yi‐Bin Pan, Yong‐Qing Cao, Chen Wang, Wei‐Dong Jiang, Wei‐Feng Zhai, Jin‐Gen Lu
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
inflammation
inflammatory bowel disease
JAK/STAT3 signaling pathway
loganin
TLR4/NF‐κB signaling pathway
Online Access:https://doi.org/10.1002/kjm2.12160

Internet

https://doi.org/10.1002/kjm2.12160

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