Targeted RNAseq Revealed the Gene Expression Signature of Ferroptosis-Related Processes Associated with Disease Severity in Patients with Multiple Sclerosis

Targeted RNAseq Revealed the Gene Expression Signature of Ferroptosis-Related Processes Associated with Disease Severity in Patients with Multiple Sclerosis

Detrimental molecular processes in multiple sclerosis (MS) lead to the cellular accumulation of lipid peroxidation products and iron in the CNS, which represents the main driving force for ferroptosis. Ferroptosis is an iron-dependent form of regulated cell death, with proposed roles in neurodegener...

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Bibliographic Details
Main Authors: Ljiljana Stojkovic, Ivan Jovanovic, Evica Dincic, Ana Djordjevic, Jovana Kuveljic, Tamara Djuric, Aleksandra Stankovic, Slobodan Vojinovic, Maja Zivkovic
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
multiple sclerosis
severity
ferroptosis
PBMCs
gene expression
targeted RNAseq
Online Access:https://www.mdpi.com/1422-0067/25/5/3016

Internet

https://www.mdpi.com/1422-0067/25/5/3016

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