The extracellular matrix protein type I collagen and fibronectin are regulated by β-arrestin-1/endothelin axis in human ovarian fibroblasts

The extracellular matrix protein type I collagen and fibronectin are regulated by β-arrestin-1/endothelin axis in human ovarian fibroblasts

Abstract Background The invasive and metastatic spread of serous ovarian cancer (SOC) results from the cooperative interactions between cancer and stroma, which include extracellular matrix (ECM) and cellular components, including cancer-associated fibroblasts (CAFs). Soluble factors secreted by can...

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Bibliografski detalji
Glavni autori: Ilenia Masi, Flavia Ottavi, Valentina Caprara, Danila Del Rio, Martina Kunkl, Francesca Spadaro, Valerio Licursi, Loretta Tuosto, Anna Bagnato, Laura Rosano’
Format: Članak
Jezik:English
Izdano: BMC 2025-02-01
Serija:Journal of Experimental & Clinical Cancer Research
Teme:
Fibroblasts
Type I collagen
Fibronectin
Endothelin-1
Ovarian cancer
Endothelin receptors
Online pristup:https://doi.org/10.1186/s13046-025-03327-5

Internet

https://doi.org/10.1186/s13046-025-03327-5

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