Constitutively active CCR5 chemokine receptors differ in mediating HIV envelope-dependent fusion.

The CCR5 chemokine receptor is a rhodopsin-like G protein-coupled receptor that mediates the effects of pro-inflammatory β-chemokines. CCR5 is also the major co-receptor for entry of human immunodeficiency virus (HIV) into human cells. G protein-coupled receptors exist in ensembles of active and ina...

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Bibliographic Details
Main Authors: Alex de Voux, Mei-Chi Chan, Asongna T Folefoc, Michael T Madziva, Colleen A Flanagan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3552960?pdf=render