Initiation of the Hypothalamic–Pituitary–Gonadal Axis in Young Girls Undergoing Central Precocious Puberty Exerts Remodeling Effects on the Prefrontal Cortex

Initiation of the Hypothalamic–Pituitary–Gonadal Axis in Young Girls Undergoing Central Precocious Puberty Exerts Remodeling Effects on the Prefrontal Cortex

Central precocious puberty (CPP) has been shown to exert significant effects on psychosocial development. These early puberty-related hormones and psychosocial functional changes are considered to be associated with specific brain development. However, the biological mechanisms underlying the sculpt...

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Bibliographic Details
Main Authors: Di Yang, Wenjing Zhang, Yaxin Zhu, Peining Liu, Bo Tao, Yuchuan Fu, Yu Chen, Lu Zhou, Lu Liu, Xin Gao, Xiaozheng Liu, Leah H. Rubin, John A. Sweeney, Zhihan Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Psychiatry
Subjects:
central precocious puberty
hypothalamic-pituitary-gonadal axis
cortical thickness
estradiol
psychological development
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2019.00332/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2019.00332/full

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