Mild systemic inflammation and moderate hypoxia transiently alter neuronal excitability in mouse somatosensory cortex

Mild systemic inflammation and moderate hypoxia transiently alter neuronal excitability in mouse somatosensory cortex

During the perinatal period, the brain is highly vulnerable to hypoxia and inflammation, which often cause white matter injury and long-term neuronal dysfunction such as motor and cognitive deficits or epileptic seizures. We studied the effects of moderate hypoxia (HYPO), mild systemic inflammation...

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Bibliographic Details
Main Authors: Jérôme Mordel, Aminah Sheikh, Simeon Tsohataridis, Patrick O. Kanold, Christoph M. Zehendner, Heiko J. Luhmann
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Neurobiology of Disease
Subjects:
Hypoxia
Systemic inflammation
Interleukin-1β
Multi-electrode array
Electrophysiology
Epileptiform activity
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115301224

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http://www.sciencedirect.com/science/article/pii/S0969996115301224

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