Inferring cell state by quantitative motility analysis reveals a dynamic state system and broken detailed balance.

Cell populations display heterogeneous and dynamic phenotypic states at multiple scales. Similar to molecular features commonly used to explore cell heterogeneity, cell behavior is a rich phenotypic space that may allow for identification of relevant cell states. Inference of cell state from cell be...

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Bibliographic Details
Main Authors: Jacob C Kimmel, Amy Y Chang, Andrew S Brack, Wallace F Marshall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5786322?pdf=render