Kinetochore Architecture Employs Diverse Linker Strategies Across Evolution

Kinetochore Architecture Employs Diverse Linker Strategies Across Evolution

The assembly of a functional kinetochore on centromeric chromatin is necessary to connect chromosomes to the mitotic spindle, ensuring accurate chromosome segregation. This connecting function of the kinetochore presents multiple internal and external structural challenges. A microtubule interacting...

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Bibliographic Details
Main Authors: Shreyas Sridhar, Tatsuo Fukagawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
chromosome segregation
mitosis
kinetochore
centromere
evolution
CCAN
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.862637/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.862637/full

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