Genetic polymorphism of interferon regulatory factor 5 (IRF5) correlates with allograft acute rejection of liver transplantation.

BACKGROUND:Although liver transplantation is one of the most efficient curative therapies of end stage liver diseases, recipients may suffer liver graft loss opst-operation. IRF-5, a member of Interferon Regulatory Factors, functions as a key regulator in TLR4 cascade, and is capable of inducing inf...

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Bibliographic Details
Main Authors: Xiaobo Yu, Bajin Wei, Yifan Dai, Min Zhang, Jian Wu, Xiao Xu, Guoping Jiang, Shusen Zheng, Lin Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4005731?pdf=render