Defining lncRNAs Correlated with CHO Cell Growth and IgG Productivity by RNA-Seq

Summary: How the long non-coding RNA (lncRNA) genome in recombinant protein producing Chinese hamster ovary (CHO) cell lines relates to phenotype is not well described. We therefore defined the CHO cell lncRNA transcriptome from cells grown in controlled miniature bioreactors under fed-batch conditi...

Full description

Bibliographic Details
Main Authors: Davide Vito, Jens Christian Eriksen, Christian Skjødt, Dietmar Weilguny, Søren K. Rasmussen, C. Mark Smales
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219305309