Platelet pannexin-1 channels modulate neutrophil activation and migration but not the progression of abdominal aortic aneurysm

Platelet pannexin-1 channels modulate neutrophil activation and migration but not the progression of abdominal aortic aneurysm

Abdominal aortic aneurysm (AAA) is a common disease and highly lethal if untreated. The progressive dilatation of the abdominal aorta is accompanied by degradation and remodeling of the vessel wall due to chronic inflammation. Pannexins represent anion-selective channels and play a crucial role in n...

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Bibliographic Details
Main Authors: Lisa Maria Metz, Tobias Feige, Larissa de Biasi, Agnes Ehrenberg, Joscha Mulorz, Laura Mara Toska, Friedrich Reusswig, Christine Quast, Norbert Gerdes, Malte Kelm, Hubert Schelzig, Margitta Elvers
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
platelets
pannexin-1
abdominal aortic aneurysm
inflammation
ECM remodeling
selectin
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1111108/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2023.1111108/full

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