Gene regulatory networks reveal sex difference in lung adenocarcinoma

Gene regulatory networks reveal sex difference in lung adenocarcinoma

Abstract Background Lung adenocarcinoma (LUAD) has been observed to have significant sex differences in incidence, prognosis, and response to therapy. However, the molecular mechanisms responsible for these disparities have not been investigated extensively. Methods Sample-specific gene regulatory n...

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Bibliographic Details
Main Authors: Enakshi Saha, Marouen Ben Guebila, Viola Fanfani, Jonas Fischer, Katherine H. Shutta, Panagiotis Mandros, Dawn L. DeMeo, John Quackenbush, Camila M. Lopes-Ramos
Format: Article
Language:English
Published: BMC 2024-08-01
Series:Biology of Sex Differences
Subjects:
Lung adenocarcinoma
Gene regulatory networks
Transcription factor
Differential targeting
Sex difference
Survival analysis
Online Access:https://doi.org/10.1186/s13293-024-00634-y

Internet

https://doi.org/10.1186/s13293-024-00634-y

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