NRBP1 modulates uric acid transporter ABCG2 expression by activating the Wnt/β-catenin pathway in HK-2 cells

Background: Nuclear receptor binding protein 1 (NRBP1) and ATP-binding cassette subfamily G member 2 (ABCG2) was the gout risk gene and high-capacity urate exporter respectively. However, the relationship between NRBP1 and ABCG2 and the underlying molecular mechanism contributing to these associatio...

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Bibliographic Details
Main Authors: Qiankun Zhang, Hang Fang, Zaihua Zhu
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Nefrología (English Edition)
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2013251422001407