RNA-Seq-based analysis of changes in Borrelia burgdorferi gene expression linked to pathogenicity

RNA-Seq-based analysis of changes in Borrelia burgdorferi gene expression linked to pathogenicity

Abstract Background Lyme disease is a global public health problem caused by the spirochaete Borrelia burgdorferi. Our previous studies found differences in disease severity between B. burgdorferi B31- and B. garinii SZ-infected mice. We hypothesized that genes that are differentially expressed betw...

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Bibliographic Details
Main Authors: Qiong Wu, Guiquan Guan, Zhijie Liu, Youquan Li, Jianxun Luo, Hong Yin
Format: Article
Language:English
Published: BMC 2015-03-01
Series:Parasites & Vectors
Subjects:
Lyme disease
Gene expression
High-throughput sequencing
Transcriptional profile
Online Access:https://doi.org/10.1186/s13071-014-0623-2

Internet

https://doi.org/10.1186/s13071-014-0623-2

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