Activation of adult mammalian retinal stem cells in vivo via antagonism of BMP and sFRP2
Abstract Background The adult mammalian retina does not have the capacity to regenerate cells lost due to damage or disease. Therefore, retinal injuries and blinding diseases result in irreversible vision loss. However, retinal stem cells (RSCs), which participate in retinogenesis during development...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-10-01
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Series: | Stem Cell Research & Therapy |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13287-021-02630-0 |