New 1,2,3-Triazole-Coumarin-Glycoside Hybrids and Their 1,2,4-Triazolyl Thioglycoside Analogs Targeting Mitochondria Apoptotic Pathway: Synthesis, Anticancer Activity and Docking Simulation

New 1,2,3-Triazole-Coumarin-Glycoside Hybrids and Their 1,2,4-Triazolyl Thioglycoside Analogs Targeting Mitochondria Apoptotic Pathway: Synthesis, Anticancer Activity and Docking Simulation

Toxicity and resistance to newly synthesized anticancer drugs represent a challenging phenomenon of intensified concern arising from variation in drug targets and consequently the prevalence of the latter concern requires further research. The current research reports the design, synthesis, and anti...

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Bibliographic Details
Main Authors: Wael A. El-Sayed, Fahad M. Alminderej, Marwa M. Mounier, Eman S. Nossier, Sayed M. Saleh, Asmaa F. Kassem
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
1,2,3-triazoles
coumarin
1,2,4-triazoles
anticancer
glycosides
molecular docking
Online Access:https://www.mdpi.com/1420-3049/27/17/5688

Internet

https://www.mdpi.com/1420-3049/27/17/5688

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