Polymorphisms in Renal Ammonia Metabolism Genes Correlate With 24-Hour Urine pH

Polymorphisms in Renal Ammonia Metabolism Genes Correlate With 24-Hour Urine pH

Urine pH is critical for net acid and solute excretion, but the genetic factors that contribute to its regulation are incompletely understood. Methods: We tested the association of single nucleotide polymorphisms (SNPs) from 16 genes related to ammonia (NH3) metabolism (15 biological candidates sele...

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Bibliographic Details
Main Authors: Benjamin K. Canales, Jennifer A. Smith, I. David Weiner, Erin B. Ware, Wei Zhao, Sharon L.R. Kardia, Gary C. Curhan, Stephen T. Turner, MD, Majuran Perinpam, BS, John C. Lieske
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Kidney International Reports
Subjects:
acid-base
diabetes mellitus
genetics
kidney stone disease
uric acid
urine pH
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024917301705

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http://www.sciencedirect.com/science/article/pii/S2468024917301705

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