Limitations of Ab initio predictions of peptide binding to MHC class II molecules.

Limitations of Ab initio predictions of peptide binding to MHC class II molecules.

Successful predictions of peptide MHC binding typically require a large set of binding data for the specific MHC molecule that is examined. Structure based prediction methods promise to circumvent this requirement by evaluating the physical contacts a peptide can make with an MHC molecule based on t...

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Bibliographic Details
Main Authors: Hao Zhang, Peng Wang, Nikitas Papangelopoulos, Ying Xu, Alessandro Sette, Philip E Bourne, Ole Lund, Julia Ponomarenko, Morten Nielsen, Bjoern Peters
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2822856?pdf=render

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http://europepmc.org/articles/PMC2822856?pdf=render

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