Lymphocyte-to-monocyte ratio as a prognostic and potential tumor microenvironment indicator in advanced soft tissue sarcoma treated with first-line doxorubicin therapy

Lymphocyte-to-monocyte ratio as a prognostic and potential tumor microenvironment indicator in advanced soft tissue sarcoma treated with first-line doxorubicin therapy

Abstract Prognostic value of hematologic indices and their association with the tumor microenvironment (TME) remain unclear in advanced soft tissue sarcoma (STS). We aimed to evaluate their prognostic value and correlation with the TME status in advanced STS treated with first-line doxorubicin (DXR)...

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Bibliographic Details
Main Authors: Sho Watanabe, Tatsunori Shimoi, Tadaaki Nishikawa, Asuka Kawachi, Hitomi Sumiyoshi Okuma, Momoko Tokura, Shu Yazaki, Chiharu Mizoguchi, Motoko Arakaki, Ayumi Saito, Shosuke Kita, Kasumi Yamamoto, Yuki Kojima, Kazuki Sudo, Emi Noguchi, Akihiko Yoshida, Akira Kawai, Yasuhiro Fujiwara, Kan Yonemori
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-37616-w

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https://doi.org/10.1038/s41598-023-37616-w

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