Unmixing for ultra-high-plex fluorescence imaging
Writing in Nature communications, Seo and collaborators presented PICASSO as a method to achieve 15-color imaging of spatially overlapping proteins using no reference emission spectra in a single staining and imaging round. This accessible tool has the potential to be applied to diverse applications...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-06-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-31110-z |
| _version_ | 1829111691707678720 |
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| author | Archibald Enninful Alev Baysoy Rong Fan |
| author_facet | Archibald Enninful Alev Baysoy Rong Fan |
| author_sort | Archibald Enninful |
| collection | DOAJ |
| description | Writing in Nature communications, Seo and collaborators presented PICASSO as a method to achieve 15-color imaging of spatially overlapping proteins using no reference emission spectra in a single staining and imaging round. This accessible tool has the potential to be applied to diverse applications within the spatial biology field without neglecting accuracy. |
| first_indexed | 2024-12-12T12:25:01Z |
| format | Article |
| id | doaj.art-716a5f4c74e240ca8beaeda87336a9e1 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-12T12:25:01Z |
| publishDate | 2022-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-716a5f4c74e240ca8beaeda87336a9e12022-12-22T00:24:34ZengNature PortfolioNature Communications2041-17232022-06-011311310.1038/s41467-022-31110-zUnmixing for ultra-high-plex fluorescence imagingArchibald Enninful0Alev Baysoy1Rong Fan2Department of Biomedical Engineering, Yale UniversityDepartment of Biomedical Engineering, Yale UniversityDepartment of Biomedical Engineering, Yale UniversityWriting in Nature communications, Seo and collaborators presented PICASSO as a method to achieve 15-color imaging of spatially overlapping proteins using no reference emission spectra in a single staining and imaging round. This accessible tool has the potential to be applied to diverse applications within the spatial biology field without neglecting accuracy.https://doi.org/10.1038/s41467-022-31110-z |
| spellingShingle | Archibald Enninful Alev Baysoy Rong Fan Unmixing for ultra-high-plex fluorescence imaging Nature Communications |
| title | Unmixing for ultra-high-plex fluorescence imaging |
| title_full | Unmixing for ultra-high-plex fluorescence imaging |
| title_fullStr | Unmixing for ultra-high-plex fluorescence imaging |
| title_full_unstemmed | Unmixing for ultra-high-plex fluorescence imaging |
| title_short | Unmixing for ultra-high-plex fluorescence imaging |
| title_sort | unmixing for ultra high plex fluorescence imaging |
| url | https://doi.org/10.1038/s41467-022-31110-z |
| work_keys_str_mv | AT archibaldenninful unmixingforultrahighplexfluorescenceimaging AT alevbaysoy unmixingforultrahighplexfluorescenceimaging AT rongfan unmixingforultrahighplexfluorescenceimaging |