Methamphetamine preconditioning alters midbrain transcriptional responses to methamphetamine-induced injury in the rat striatum.

Methamphetamine (METH) is an illicit drug which is neurotoxic to the mammalian brain. Numerous studies have revealed significant decreases in dopamine and serotonin levels in the brains of animals exposed to moderate-to-large METH doses given within short intervals of time. In contrast, repeated inj...

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Bibliographic Details
Main Authors: Jean Lud Cadet, Michael T McCoy, Ning Sheng Cai, Irina N Krasnova, Bruce Ladenheim, Genevieve Beauvais, Natascha Wilson, William Wood, Kevin G Becker, Amber B Hodges
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2771908?pdf=render