Trilayered biomimetic hydrogel scaffolds with dual-differential microenvironment for articular osteochondral defect repair

Commonly, articular osteochondral tissue exists significant differences in physiological architecture, mechanical function, and biological microenvironment. However, the development of biomimetic scaffolds incorporating upper cartilage, middle tidemark-like, and lower subchondral bone layers for pre...

Full description

Bibliographic Details
Main Authors: Hongying Chen, Jinyi Huang, Xiaomeng Li, Weiwei Zhao, Yujie Hua, Zhenfeng Song, Xianwei Wang, Zhikun Guo, Guangdong Zhou, Wenjie Ren, Yongkun Sun
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Materials Today Bio
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424001108