KISS1R and ANKRD31 Cooperate to Enhance Leydig Cell Gene Expression via the Cytoskeletal-Nucleoskeletal Pathway

Kisspeptins are involved in the regulation of hypothalamic-pituitary-gonadal axis, Leydig cell functions, and testosterone secretion, acting as endogenous ligands of the KISS1 receptor. ANKRD31 protein participates in male fertility, regulating meiotic progression, and epididymal sperm maturation. H...

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Bibliographic Details
Main Authors: Giulia Ricci, Florian Guillou, Angela Catizone, Vincenza Grazia Mele, Martina Moggio, Teresa Chioccarelli, Nadia Diano, Rosaria Meccariello, Riccardo Pierantoni, Silvia Fasano, Gilda Cobellis, Rosanna Chianese, Francesco Manfrevola
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.877270/full