Mechanisms of Alpha-Synuclein Action on Neurotransmission: Cell-Autonomous and Non-Cell Autonomous Role

Mutations and duplication/triplication of the alpha-synuclein (αSyn)-coding gene have been found to cause familial Parkinson’s disease (PD), while genetic polymorphisms in the region controlling the expression level and stability of αSyn have been identified as risk factors for idiopathic PD, pointi...

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Bibliographic Details
Main Authors: Marco Emanuele, Evelina Chieregatti
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/5/2/865