Induction of Mitochondrial Fragmentation and Mitophagy after Neonatal Hypoxia–Ischemia

Induction of Mitochondrial Fragmentation and Mitophagy after Neonatal Hypoxia–Ischemia

Hypoxia–ischemia (HI) leads to immature brain injury mediated by mitochondrial stress. If damaged mitochondria cannot be repaired, mitochondrial permeabilization ensues, leading to cell death. Non-optimal turnover of mitochondria is critical as it affects short and long term structural and functiona...

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Bibliographic Details
Main Authors: Syam Nair, Anna-Lena Leverin, Eridan Rocha-Ferreira, Kristina S. Sobotka, Claire Thornton, Carina Mallard, Henrik Hagberg
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
mitochondria
metabolism
mitochondrial fission
neonatal brain injury
reactive oxygen species
neonatal hypoxia–ischemia
Online Access:https://www.mdpi.com/2073-4409/11/7/1193

Internet

https://www.mdpi.com/2073-4409/11/7/1193

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