Sodium Butyrate Attenuates Taurocholate-Induced Acute Pancreatitis by Maintaining Colonic Barrier and Regulating Gut Microorganisms in Mice

Sodium Butyrate Attenuates Taurocholate-Induced Acute Pancreatitis by Maintaining Colonic Barrier and Regulating Gut Microorganisms in Mice

BackgroundAcute pancreatitis (AP) damages the intestinal barrier, which aggravates AP. Butyrate exhibits anti-inflammatory effects in AP, but it is unknown if such a protective effect is associated with the regulation of gut microorganisms. We aim to investigate the effects of sodium butyrate (SB) o...

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Bibliographic Details
Main Authors: Yangyang Xiong, Li Ji, Yi Zhao, Ailing Liu, Dong Wu, Jiaming Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Physiology
Subjects:
acute pancreatitis
sodium butyrate
pancreas
colon
neutrophils
macrophages
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.813735/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.813735/full

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