Functional Analyses of Bovine Foamy Virus-Encoded miRNAs Reveal the Importance of a Defined miRNA for Virus Replication and Host–Virus Interaction

Functional Analyses of Bovine Foamy Virus-Encoded miRNAs Reveal the Importance of a Defined miRNA for Virus Replication and Host–Virus Interaction

In addition to regulatory or accessory proteins, some complex retroviruses gain a repertoire of micro-RNAs (miRNAs) to regulate and control virus–host interactions for efficient replication and spread. In particular, bovine and simian foamy viruses (BFV and SFV) have recently been shown to express a...

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Bibliographic Details
Main Authors: Wenhu Cao, Erik Stricker, Agnes Hotz-Wagenblatt, Anke Heit-Mondrzyk, Georgios Pougialis, Annette Hugo, Jacek Kuźmak, Magdalena Materniak-Kornas, Martin Löchelt
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Viruses
Subjects:
bovine foamy virus
spumaretrovirus
miRNA expression
virus-host-interaction
miRNA target gene identification
innate immunity
Online Access:https://www.mdpi.com/1999-4915/12/11/1250

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https://www.mdpi.com/1999-4915/12/11/1250

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