Phase Separation Investigation of Axitinib in Supersaturated Solution

Phase Separation Investigation of Axitinib in Supersaturated Solution

Phase separation is quite common in formulations for hydrophobic active pharmaceutical ingredients (APIs) due to their thermodynamic instability in a supersaturated state during in vitro dissolution or in vivo absorption. Phase separation possibly accompanies the formation of a disordered drug-rich...

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Bibliographic Details
Main Authors: Jie Xu, Jianshuo Su, Huaizhen Zhang, Rupeng Bu, Zhuang Ding, Ning Zhang, Yanna Zhao
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Crystals
Subjects:
phase separation
axitinib
supersaturated state
dynamic light scattering
UV-vis extinction
Online Access:https://www.mdpi.com/2073-4352/14/12/1042

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https://www.mdpi.com/2073-4352/14/12/1042

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