Association of DRD2, DRD4 and COMT genes variants and their gene-gene interactions with antipsychotic treatment response in patients with schizophrenia

Abstract Antipsychotic drugs are the first line of treatment in schizophrenia; although antipsychotic responses indicate a wide interindividual variety in patients with schizophrenia. This study aimed to investigate the association between four polymorphisms in DRD2, DRD4 and COMT genes and their ge...

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Bibliographic Details
Main Authors: Narges Taheri, Rokhshid Pirboveiri, Mehdi Sayyah, Mahdi Bijanzadeh, Pegah Ghandil
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Psychiatry
Subjects:
Online Access:https://doi.org/10.1186/s12888-023-05292-9