LRRC8A promotes the initial development of oxaliplatin resistance in colon cancer cells

LRRC8A promotes the initial development of oxaliplatin resistance in colon cancer cells

Leucine-rich repeat-containing 8 A (LRRC8A) is an essential component of the volume-regulated anion channel (VRAC), which plays a vital role in cell proliferation, migration, apoptosis, and drug resistance. In this study, we investigated the effects of LRRC8A on oxaliplatin resistance in colon cance...

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Bibliographic Details
Main Authors: Haifeng Zhang, Zhenghui Jing, Rong Liu, Yassin Shada, Sindhwani Shria, Shiyu Cui, Yuhua Ren, Yuan Wei, Liangming Li, Shuang Peng
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Heliyon
Subjects:
Colon cancer
VRAC
LRRC8A
Drug resistance
Oxaliplatin
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023040793

Internet

http://www.sciencedirect.com/science/article/pii/S2405844023040793

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