Long-Term Motor Cortical Electrical Stimulation Ameliorates 6-Hydroxydopamine-Induced Motor Dysfunctions and Exerts Neuroprotective Effects in a Rat Model of Parkinson’s Disease

Long-Term Motor Cortical Electrical Stimulation Ameliorates 6-Hydroxydopamine-Induced Motor Dysfunctions and Exerts Neuroprotective Effects in a Rat Model of Parkinson’s Disease

ObjectiveCortical electrical stimulation (CES) can modulate cortical excitability through a plasticity-like mechanism and is considered to have therapeutic potentials in Parkinson’s disease (PD). However, the precise therapeutic value of such approach for PD remains unclear. Accordingly, we adopted...

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Bibliographic Details
Main Authors: Chi-Wei Kuo, Ming-Yuan Chang, Ming-Yi Chou, Chien-Yuan Pan, Chih-Wei Peng, Hui-Chiun Tseng, Tsu-Yi Jen, Xiao-Kuo He, Hui-Hua Liu, Thi Xuan Dieu Nguyen, Pi-Kai Chang, Tsung-Hsun Hsieh
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
cortical electrical stimulation
Parkinson’s disease
gait
locomotor function
neuroprotection
6-OHDA
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.848380/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2022.848380/full

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