Sonic Hedgehog Signaling Promotes Peri-Lesion Cell Proliferation and Functional Improvement after Cortical Contusion Injury

Sonic Hedgehog Signaling Promotes Peri-Lesion Cell Proliferation and Functional Improvement after Cortical Contusion Injury

Traumatic brain injury (TBI) is a leading cause of death and disability globally. No drug treatments are available, so interest has turned to endogenous neural stem cells (NSCs) as alternative strategies for treatment. We hypothesized that regulation of cell proliferation through modulation of the s...

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Bibliographic Details
Main Authors: Ashley K. Pringle, Elshadaie Solomon, Benjamin J. Coles, Brandon R. Desousa, Anan Shtaya, Shyam Gajavelli, Nedal Dabab, Malik J. Zaben, Diederik O. Bulters, M. Ross Bullock, Aminul I. Ahmed
Format: Article
Language:English
Published: Mary Ann Liebert 2021-01-01
Series:Neurotrauma Reports
Subjects:
cerebral cortex
endogenous stem cells
motor recovery
sonic hedgehog
traumatic brain injury
Online Access:https://www.liebertpub.com/doi/full/10.1089/NEUR.2020.0016

Internet

https://www.liebertpub.com/doi/full/10.1089/NEUR.2020.0016

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