Boosting with adjuvanted SCB-2019 elicits superior Fcγ-receptor engagement driven by IgG3 to SARS-CoV-2 spike

Abstract With the continued emergence of variants of concern, the global threat of COVID-19 persists, particularly in low- and middle-income countries with limited vaccine access. Protein-based vaccines, such as SCB-2019, can be produced on a large scale at a low cost while antigen design and adjuva...

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Bibliographic Details
Main Authors: Wonyeong Jung, Dansu Yuan, Benjamin Kellman, Isabela Garrido da Silva Gonzalez, Ralf Clemens, Eveline Pipolo Milan, Eduardo Sprinz, José Cerbino Neto, Igor Smolenov, Galit Alter, Ryan P. McNamara, Sue Ann Costa Clemens
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00791-y