Celecoxib Suppresses NF-κB p65 (RelA) and TNFα Expression Signaling in Glioblastoma

Celecoxib Suppresses NF-κB p65 (RelA) and TNFα Expression Signaling in Glioblastoma

Background: Glioblastoma (GBM) harbors significant genetic heterogeneity, high infiltrative capacity, and patterns of relapse following many therapies. The expression of nuclear factor kappa-B (NF-κB p65 (RelA)) and signaling pathways is constitutively activated in GBM through inflammatory stimulati...

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Bibliographic Details
Main Authors: Hina Ahsan, Shaukat Iqbal Malik, Fawad Ali Shah, Hamed A. El-Serehy, Amin Ullah, Zafar Abbas Shah
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Journal of Clinical Medicine
Subjects:
glioblastoma
gene expression genes
tumor necrosis factor
survival analysis
celecoxib
temozolomide
Online Access:https://www.mdpi.com/2077-0383/12/20/6683

Internet

https://www.mdpi.com/2077-0383/12/20/6683

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