Mitochondria hormesis delays aging and associated diseases in Caenorhabditis elegans impacting on key ferroptosis players

Mitochondria hormesis delays aging and associated diseases in Caenorhabditis elegans impacting on key ferroptosis players

Summary: Excessive iron accumulation or deficiency leads to a variety of pathologies in humans and developmental arrest in the nematode Caenorhabditis elegans. Instead, sub-lethal iron depletion extends C. elegans lifespan. Hypoxia preconditioning protects against severe hypoxia-induced neuromuscula...

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Bibliographic Details
Main Authors: Alfonso Schiavi, Eva Salveridou, Vanessa Brinkmann, Anjumara Shaik, Ralph Menzel, Sumana Kalyanasundaram, Ståle Nygård, Hilde Nilsen, Natascia Ventura
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:iScience
Subjects:
Cellular physiology
Cellular neuroscience
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223005254

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http://www.sciencedirect.com/science/article/pii/S2589004223005254

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