Arachidonic acid drives postnatal neurogenesis and elicits a beneficial effect on prepulse inhibition, a biological trait of psychiatric illnesses.

Arachidonic acid drives postnatal neurogenesis and elicits a beneficial effect on prepulse inhibition, a biological trait of psychiatric illnesses.

Prepulse inhibition (PPI) is a compelling endophenotype (biological markers) for mental disorders including schizophrenia. In a previous study, we identified Fabp7, a fatty acid binding protein 7 as one of the genes controlling PPI in mice and showed that this gene was associated with schizophrenia....

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Main Authors: Motoko Maekawa, Noriko Takashima, Miho Matsumata, Shiro Ikegami, Masanori Kontani, Yoshinobu Hara, Hiroshi Kawashima, Yuji Owada, Yoshinobu Kiso, Takeo Yoshikawa, Kaoru Inokuchi, Noriko Osumi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2663848?pdf=render

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http://europepmc.org/articles/PMC2663848?pdf=render

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