uL3 Regulates Redox Metabolism and Ferroptosis Sensitivity of p53-Deleted Colorectal Cancer Cells

uL3 Regulates Redox Metabolism and Ferroptosis Sensitivity of p53-Deleted Colorectal Cancer Cells

Despite advancements in therapeutic strategies, the development of drug resistance and metastasis remains a serious concern for the efficacy of chemotherapy against colorectal cancer (CRC). We have previously demonstrated that low expression of ribosomal protein uL3 positively correlates with chemor...

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Bibliographic Details
Main Authors: Chiara Brignola, Annalisa Pecoraro, Camilla Danisi, Nunzia Iaccarino, Anna Di Porzio, Francesca Romano, Pietro Carotenuto, Giulia Russo, Annapina Russo
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Series:Antioxidants
Subjects:
drug resistance
cancer redox metabolic reprogramming
SLC7A11/xCT
ferroptosis
ribosomal protein uL3
CAM assay
Online Access:https://www.mdpi.com/2076-3921/13/7/757

Internet

https://www.mdpi.com/2076-3921/13/7/757

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