Deregulation of cell growth and apoptosis in UV-induced melanomagenesis

Deregulation of cell growth and apoptosis in UV-induced melanomagenesis

We have previously characterized the role of p16/Rb in coordinating the early events in UVB-irradiated skin. As an extension to this work, normal melanocytes and mutant p16-inducible melanoma cell models were employed to elucidate further the coordinated molecular mechanisms occurring during early U...

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Bibliographic Details
Main Authors: Allal Ouhtit, Ishita Gupta, Rajiv L. Gaur, Augusta Fernando, Amira O. Abd El-Azim, Ali Eid, Therese M Becker
Format: Article
Language:English
Published: IMR Press 2020-03-01
Series:Frontiers in Bioscience-Elite
Subjects:
melanoma
p16ink4a/rb pathway
cell cycle
apoptosis
uvb irradiation.
Online Access:https://www.imrpress.com/journal/FBE/12/2/10.2741/E868

Internet

https://www.imrpress.com/journal/FBE/12/2/10.2741/E868

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