Enhancing menaquinone-7 biosynthesis by adaptive evolution of Bacillus natto through chemical modulator

Abstract Menaquinone-7 (MK-7) is a kind of vitamin K2 playing an important role in the treatment and prevention of cardiovascular disease, osteoporosis and arterial calcification. The purpose of this study is to establish an adaptive evolution strategy based on a chemical modulator to improve MK-7 b...

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Bibliographic Details
Main Authors: Bei Zhang, Cheng Peng, Jianyao Lu, Xuechao Hu, Lujing Ren
Format: Article
Language:English
Published: SpringerOpen 2022-11-01
Series:Bioresources and Bioprocessing
Subjects:
Online Access:https://doi.org/10.1186/s40643-022-00609-0