Immunogenicity of MultiTEP platform technology-based Tau vaccine in non-human primates

Abstract Pathological forms of Tau protein are directly associated with neurodegeneration and correlate with Alzheimer’s Disease (AD) symptoms, progression, and severity. Previously, using various mouse models of Tauopathies and AD, we have demonstrated the immunogenicity and efficacy of the MultiTE...

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Bibliographic Details
Main Authors: Armine Hovakimyan, Karen Zagorski, Gor Chailyan, Tatevik Antonyan, Levon Melikyan, Irina Petrushina, Dash G. Batt, Olga King, Manush Ghazaryan, Aashrit Donthi, Caitlynn Foose, Nikolai Petrovsky, David H. Cribbs, Michael G. Agadjanyan, Anahit Ghochikyan
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-022-00544-3