Resting-state fMRI reveals longitudinal alterations in brain network connectivity in the zQ175DN mouse model of Huntington's disease

Resting-state fMRI reveals longitudinal alterations in brain network connectivity in the zQ175DN mouse model of Huntington's disease

Huntington's disease is an autosomal, dominantly inherited neurodegenerative disease caused by an expansion of the CAG repeats in exon 1 of the huntingtin gene. Neuronal degeneration and dysfunction that precedes regional atrophy result in the impairment of striatal and cortical circuits that a...

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Bibliographic Details
Main Authors: Tamara Vasilkovska, Mohit H. Adhikari, Johan Van Audekerke, Somaie Salajeghe, Dorian Pustina, Roger Cachope, Haiying Tang, Longbin Liu, Ignacio Muñoz-Sanjuán, Annemie Van der Linden, Marleen Verhoye
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Neurobiology of Disease
Subjects:
Huntington's disease
Functional connectivity
Large-scale brain networks
Resting-state fMRI
Neurodegeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996123001092

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http://www.sciencedirect.com/science/article/pii/S0969996123001092

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