TMEM266 is a functional voltage sensor regulated by extracellular Zn2+

TMEM266 is a functional voltage sensor regulated by extracellular Zn2+

Voltage-activated ion channels contain S1-S4 domains that sense membrane voltage and control opening of ion-selective pores, a mechanism that is crucial for electrical signaling. Related S1-S4 domains have been identified in voltage-sensitive phosphatases and voltage-activated proton channels, both...

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Bibliographic Details
Main Authors: Ferenc Papp, Suvendu Lomash, Orsolya Szilagyi, Erika Babikow, Jaime Smith, Tsg-Hui Chang, Maria Isabel Bahamonde, Gilman Ewan Stephen Toombes, Kenton Jon Swartz
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-02-01
Series:eLife
Subjects:
S1-S4 domain
voltage-sensing domain
divalent cations
fluorescence
fluorimetry
Online Access:https://elifesciences.org/articles/42372

Internet

https://elifesciences.org/articles/42372

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