TMEM266 is a functional voltage sensor regulated by extracellular Zn2+
Voltage-activated ion channels contain S1-S4 domains that sense membrane voltage and control opening of ion-selective pores, a mechanism that is crucial for electrical signaling. Related S1-S4 domains have been identified in voltage-sensitive phosphatases and voltage-activated proton channels, both...
Main Authors: | Ferenc Papp, Suvendu Lomash, Orsolya Szilagyi, Erika Babikow, Jaime Smith, Tsg-Hui Chang, Maria Isabel Bahamonde, Gilman Ewan Stephen Toombes, Kenton Jon Swartz |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/42372 |
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