Navigating PRKCSH’s impact on cancer: from N-linked glycosylation to death pathway and anti-tumor immunity

PRKCSH, also known as Glucosidase II beta subunit (GluIIβ), is a crucial component of the endoplasmic reticulum (ER) quality control system for N-linked glycosylation, essential for identifying and eliminating misfolded proteins. Glucosidase II consists of the catalytic alpha subunit (GluIIα) and th...

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Bibliographic Details
Main Authors: Ratchada Cressey, Moe Thi Thi Han, Worapong Khaodee, Guo Xiyuan, Yuan Qing
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1378694/full