Activation of complement C1q and C3 in glomeruli might accelerate the progression of diabetic nephropathy: Evidence from transcriptomic data and renal histopathology

ABSTRACT Aims/Introduction It is not unclear whether the complement system is involved in the pathogenesis of diabetic nephropathy (DN). We explored the role of the complement system in glomeruli from patients with DN using integrated transcriptomic bioinformatics analysis and renal histopathology....

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Bibliographic Details
Main Authors: Yuanyuan Jiao, Shimin Jiang, Ying Wang, Tianyu Yu, Guming Zou, Li Zhuo, Wenge Li
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Journal of Diabetes Investigation
Subjects:
Online Access:https://doi.org/10.1111/jdi.13739