CTEN induces epithelial-mesenchymal transition (EMT) and metastasis in non small cell lung cancer cells.

To explore the effects and mechanism of CTEN (COOH-terminus tensin-like molecule) on EMT, cell migration and invasion of Human lung adenocarcinoma cells. The pCMV-vector, pCMV-CTEN, Control-shRNA, and CTEN-shRNA were transfected into A549 and NCI-H1299 cells by Lipofectamine 2000. Transforming growt...

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Bibliographic Details
Main Authors: Xiangdong Lu, Juan Gao, Yao Zhang, Tao Zhao, Hongchuan Cai, Tingrong Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6037349?pdf=render