Myocardial deletion of Smad4 using a novel α skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tract
<p>SMAD4 acts as the converging point for TGFβ and BMP signaling in heart development. Here, we investigated the role of SMAD4 in heart development using a novel α skeletal muscle actin Cre recombinase (<i>MuCre</i>) transgenic mouse strain. Lineage tracing using...
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| Format: | Article |
| Language: | English |
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Ivyspring International Publisher
2010-01-01
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| Series: | International Journal of Biological Sciences |
| Online Access: | http://www.biolsci.org/v06p0546.htm |