Myocardial deletion of Smad4 using a novel α skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tract

Myocardial deletion of Smad4 using a novel α skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tract

<p>SMAD4 acts as the converging point for TGFβ and BMP signaling in heart development. Here, we investigated the role of SMAD4 in heart development using a novel α skeletal muscle actin Cre recombinase (<i>MuCre</i>) transgenic mouse strain. Lineage tracing using...

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Bibliographic Details
Main Author:	Mohamad Azhar, Pei-Yu Wang, Tony Frugier, Kyoko Koishi, Chuxia Deng, Peter G. Noakes, Ian S. McLennan
Format:	Article
Language:	English
Published:	Ivyspring International Publisher 2010-01-01
Series:	International Journal of Biological Sciences
Online Access:	http://www.biolsci.org/v06p0546.htm

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