Differential regulation of type I interferon and epidermal growth factor pathways by a human Respirovirus virulence factor.

A number of paramyxoviruses are responsible for acute respiratory infections in children, elderly and immuno-compromised individuals, resulting in airway inflammation and exacerbation of chronic diseases like asthma. To understand the molecular pathogenesis of these infections, we searched for cellu...

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Main Authors: Grégory Caignard, Anastassia V Komarova, Mehdi Bouraï, Thomas Mourez, Yves Jacob, Louis M Jones, Flore Rozenberg, Astrid Vabret, François Freymuth, Frédéric Tangy, Pierre-Olivier Vidalain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19806178/pdf/?tool=EBI