Dietary Choline Protects Against Cognitive Decline After Surgery in Mice

Perioperative neurocognitive disorders (PNDs) are a common complication following procedures such as orthopedic surgery. Using a mouse model of tibial fracture and repair surgery, we have previously shown an increase in neuroinflammation and hippocampal-dependent cognitive deficits. These changes we...

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Bibliographic Details
Main Authors: Sara V. Maurer, Cuicui Kong, Niccolò Terrando, Christina L. Williams
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.671506/full